| 订购货号 | 产品名称及规格 | 价格(¥) |
| 21860 | TFA-Amino modifier CPG 500, 250 mg | 1560.00 |
| 41860 | TFA-Amino modifier CPG 500, 1 g | 4940.00 |
| 51860 | TFA-Amino modifier CPG 500, 5 g | 21450.00 |
This high load, 500 Å controlled pore glass solid support is designed for the synthesis of oligonucleotides containing up to 50 bases with a 3'-amino group. Amino group is protected with trifluoroacetyl (TFA) protection which is easily removed under standard deblock conditions.
The reagent is based on hydroxyprolinol core - a universal non-nucleoside structure that is naturally 100% chiral (no isomers formed upon condensation), and stable to all conditions of oligonucleotide synthesis and deblock.
General properties
|
Appearance: |
off-white beads |
|
Quality control: |
NMR 1H and HPLC (95%) of bound reagent, loading measurement |
|
Storage conditions: |
Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. |
CPG details
|
Pore size, Å: |
500 |
|
Typical loading, umol/g: |
70−90 |
|
Coupling conditions: |
standard coupling, identical to normal nucleobases |
|
Cleavage conditions: |
ammonia, 2 h at room temperature |
|
Deprotection conditions: |
identical to protected nucleobases |